Rovati 1997.

Methods	Randomized controlled trial Double blinded Multicenter Parallel group This study is unpublished at this time (the authors have provided us data from this study in the form of a full manuscript ). Preliminary data from the study were also presented in abstract form by Rovati LC, 1997
Participants	Outpatients with primary osteoarthritis of the knee Country: France N = 319 Mean age: 65.5 years Female: 75% Male: 25% Age range = 45‐85 years
Interventions	GS 1500 mg per day versus piroxicam 20 mg per day versus the combination of the two versus double placebo Duration 12 weeks of treatment and 8 weeks of follow up
Outcomes	Lequesne Index Pain (VAS) Safety
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate