Figure 3.

Corticosterone-induced mineralocorticoid receptor transactivation in A, CV1-rMR MMTV-Gluc.tet-inducible-r11βHSD2, and B, CHO-rMR-pBM14-pTAT3-Gluc.tet-inducible-r11βHSD2cells assessed by a Gaussia luciferase reporter gene system. Results are shown as mean ± SEM. *P less than .05 vs the same concentration of corticosterone in control cells without doxycycline (doxy). Mean values based on data from quadruplicate wells for each concentration of steroids from 3 separate experiments were plotted and expressed as fold over control.