Table 4.
Comparison of activated voxel of primary olfactory cortex (POC) in three groups under two odors.
| Odor type | Concentration | NC (n = 25) | MCI (n = 26) | AD (n = 22) | H | p |
|---|---|---|---|---|---|---|
| Activation voxel numbers [P 50 (P 25 – P 75 )] | ||||||
| PO | 0.10% | 23.00 (3.50–58.50)∧* | 2.50 (0.00–14.25)* | 0.00 (0.00–0.00)∧ | 20.427 | 0.000 |
| 0.33% | 33.00 (5.00–66.50)∧* | 0.50 (0.00–40.75)* | 0.00 (0.00–0.00)∧ | 19.314 | 0.000 | |
| 1.00% | 21.00 (0.00–45.00) | 9.00 (0.00–47.50)# | 0.00 (0.00–19.25)# | 7.139 | 0.028 | |
| UPO | 0.10% | 42.00 (2.50–86.50)∧* | 4.00 (0.00–21.50)* | 0.00 (0.00–0.00)∧ | 20.930 | 0.000 |
| 0.33% | 35.00 (3.00–63.00)∧ | 15.50 (0.00–37.50)# | 0.00 (0.00–10.5)∧# | 15.266 | 0.000 | |
| 1.00% | 15.00 (0.00–39.00)∧ | 2.50 (0.00–64.25) | 0.00 (0.00–21.25)∧ | 6.818 | 0.033 | |
PO, pleasant odor; UPO, unpleasant odor; NC, normal control; MCI, mild cognitive impairment; AD, Alzheimer's disease; H, Kruskal–Wallis rank sum test.
Bonferroni post-hoc tests among the three groups.
*
Significant difference between NC and MCI groups.
#
Significant difference between MCI and AD groups.
∧
Significant difference between NC and AD groups.