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. 2021 Sep 9;11:732447. doi: 10.3389/fonc.2021.732447

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Copyright © 2021 Zhang, Liu, Li, Liu, Wang, Han and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular landscape, immune landscape, and assessment of chemotherapy. (A, B) The GSEA analysis of the high- and low-risk groups. (A) The KEGG pathway enrichment analysis and (B) The biology process enrichment analysis. (C) The heatmap of the clinical- and immune-related molecular landscape. From the top to the end, there are five models, including clinical characteristics, immune cells, B7-CD28, TNF superfamily, and other immune-related molecular landscapes. (D) Molecular regulatory mechanism of the seven potential antitumour drugs. Left, the drug names and the level of sensitivity in each group; middle, the drug-targeted molecules; right, the drug-targeted pathways.