Table 1.
Baseline characteristics of the study population across the two surges
| First surge (until 26 May 2020) | Second surge 1 September–31 December 2020 |
p value First surge versus second surge |
|||
|---|---|---|---|---|---|
| Patients (n) | 1327 | 1298 | |||
| Characteristics | Missing values (N) | Missing values (N) | |||
| Age (years) | 74 (72–78) | 4 | 75 (72–79) | 1 | 0.02 |
| Sex (male sex) | 74% | 4 | 70% | 1 | 0.04 |
| Weight (kg) | 80 (72–90) | 107 | 80 (72–91) | 45 | 0.30 |
| Height (cm) | 170 (165–177) | 142 | 170 (164–177) | 67 | 0.12 |
| BMI (kg/m2) | 27.5 (24.7–30.1) | 154 | 27.6 (24.9–31.1) | 77 | 0.03 |
| Clinical status | |||||
| CFS | 3 (2–4) | 114 | 3 (2–4) | 116 | 0.0011 |
| SOFA | 6 (3–8) | 13 | 5 (3–7) | 28 | < 0.0001 |
| PaO2/FiO2 ratio | 126 (84–181) | 18 | 104 (75–156) | 63 | < 0.0001 |
| Comorbidities | |||||
| Diabetes mellitus (%) | 31% | 8 | 36% | 10 | 0.0097 |
| Ischemic heart disease (%) | 20% | 22 | 25% | 17 | 0.0004 |
| Chronic kidney disease (%) | 15% | 14 | 17% | 14 | 0.22 |
| Arterial hypertension (%) | 66% | 9 | 67% | 8 | 0.52 |
| Chronic pulmonary disease (%) | 22% | 16 | 23% | 9 | 0.45 |
| Chronic heart failure (%) | 14% | 22 | 15% | 17 | 0.72 |
| Habitat categories | |||||
| Own home | 78% | 0 | 80% | 0 | 0.0001 |
| Other home with family or caregivers | 6% | 0 | 6% | 0 | |
| Nursing home | 4% | 0 | 2% | 0 | |
| Hospital ward | 6% | 0 | 8% | 0 | |
| Other/Unknown | 6% | 0 | 4% | 0 |