Table II.

Associations of SPHK1 expression with the clinicopathological features of patients with ESCC.

Features	n	SPHK1 expression		χ2	P-value
		+	−
Sex				0.526	0.468
Male	55	32	23
Female	30	15	15
Age, years				1.746	0.186
<60	38	18	20
≥60	47	29	18
Smoking				0.337	0.562
Yes	41	24	17
No	44	23	21
Drinking				1.646	0.200
Yes	49	30	19
No	36	17	19
Tumor diameter, cm				2.031	0.154
<4	51	25	26
≥4	34	22	12
Differentiation degree				0.616	0.433
High/moderate	52	27	25
Poor	33	20	13
Tumor-Node-Metastases stage				8.567	0.003a
I-II	55	24	31
III-IV	30	23	7
Lymph node metastasis				6.559	0.010a
Yes	28	21	7
No	57	26	31

^aP≤0.01.