Table 5.
Hematochemical parameters: Endocrine parameters.
| Variable (unit of measurement) |
(a) Young Adults (18-39 y.o.) N=29; M=13; W=16 |
(b) Adults (40-64 y.o.) N=40; M=21; W=19 |
(c) Older adults (65-89 y.o.) N=54; M=28; W=26 |
(d) Nonagenarians (90-99) y.o. N=27; M=9; W=18 |
(e) Centenarians (100-111) y.o. N=23; M=6; W=17 |
Age | Interaction | Gender | |
|---|---|---|---|---|---|---|---|---|---|
| M | W | ||||||||
| TSH (µIU/mL, 0.27-4,2) |
2.07 (0.59-6.06) N=29, (2.21±1.09) M=13, (2.47±1.23) W=16, (2.00±0.95) |
1.74 (0.31-4.67) N=40, (1.88±0.89) M=21, (2.05±1.02) W=19, (1.70±0.71) |
1.69 (0.39-7.72) N=54, (2.05±1.40) M=28, (1.94±1.28) W=25, (2.17±1.53) |
1.50 (0.01-9.94) N=26, (2.08±2.30) M=9, (2.29±2.47) W=17, (1.96±2.27) |
1.70 (0.73-10.70) N=23, (2.53±2.15) M=6, (1.92±1.05) W=17, (2.75±2.41) |
ns | ns | ns | ns |
| FT3 (pg/mL, 2-4.4) |
3.09 (2.21-3.85) N=29, (3.15±0.40) M=13, (3.25±0.41) W=16, (3.08±0.39) |
3.12 (2.40-4.27) N=40, (3.20±0.38) M=21, (3.28±0.32) W=19, (3.11±0.42) |
3.03 (2.19-3.69) N=54, (3.04±0.32) M=28, (3.06±0.28) W=26, (3.03±0.37) |
2.80 (1.80-4.08) N=27, (2.76±0.56) M=9, (2.85±0.58) W=18, (2.72±0.57) |
2.54 (1.90-3.58) N=23, (2.58±0.46) M=6, (2.73±0.22) W=17, (2.52±0.51) |
(a vs d,e) (b vs d,e) (c vs e) |
ns | ns | =0.04 |
| FT4 (ng/dL, 0.93-1.7) |
1.28 (0.98-1.65) N=29, (1.30±0.16) M=13, (1.37±0.18) W=16, (1.24±0.13) |
1.17 (0.94-1.68) N=36, (1.20±0.17) M=19, (1.16±0.16) W=17, (1.25±0.17) |
1.15 (0.77-1.80) N=52, (1.16±0.20) M=27, (1.15±0.21) W=25, (1.17±0.19) |
1.18 (0.88-1.89) N=25, (1.24±0.23) M=9, (1.13±0.20) W=16, (1.30±0.23) |
1.17 (0.94-1.56) N=20, (1.21±0.17) M=4, (1.30±0.26) W=16, (1.19±0.14) |
(a vs c) | (a vs c) | ns | ns |
| Insulin (µU/mL, 2.6-24.9) |
5.66 (2.48-15.40) N=29, (6.98±3.44) M=13, (7.49±3.80) W=16, (6.57±3.19) |
9.23 (3.05-36.10) N=40, (10.49±6.97) M=21, (11.81±8.52) W=19, (9.04±4.51) |
9.71 (3.80-49.40) N=54, (14.68±14.94) M=27, (14.68±17.42) W=26, (14.69±12.05) |
6.22 (1.33-15.70) N=27, (9.65±15.73) M=9, (6.65±3.01) W=17, (11.14±19.15) |
5.04 (2.50-23.10) N=23, (7.40±5.80) M=6, (9.32±7.19) W=17, (6.73±5.31) |
(a vs c) | ns | ns | ns |
| HOMA index (0.23-2.5) |
1.20 (0.47-3.19) N=29, (1.42±0.77) M=13, (1.57±0.88) W=16, (1.31±0.68) |
2.06 (0.55-13.55) N=40, (2.55±2.43) M=21, (3.04±3.09) W=19, (2.01±1.24) |
2.20 (0.80-38.83) N=53, (3.86±5.62) M=28, (4.06±6.97) W=25, (3.64±3.69) |
1.32 (0.25-25.02) N=27, (2.30±4.61) M=9, (1.56±1.01) W=18, (2.67±5.62) |
1.09 (0.53-5.76) N=23, (1.69±1.46) M=6, (2.14±1.85) W=17, (1.53±1.33) |
ns | ns | ns | ns |
| Glycaemia (mg/dL, 70-100) |
81 (65-98) N=29, (81.07±6.63) M=13, (82.69±8.29) W=16, (79.75±4.78) |
88 (74-152) N=40, (91.43±16.14) M=21, (95.52±18.90) W=19, (86.89±11.21) |
93.5 (63-207) N=54, (98.24±21.71) M=28, (98.64±16.12) W=26, (97.81±26.80) |
84 (65-147) N=27, (86.78±16.00) M=9, (90.33±21.90) W=18, (85±12.48) |
89 (72-108) N=23, (89.13±9.25) M=6, (89.83±6.62) W=17, (88.88±10.19) |
(a vs c) |
ns | ns | ns |
Abbreviations: y.o.=years old; N=total number of cases; M=men; W=women; SD=standard deviation; TSH=thyroid-stimulating hormone; FT3=free triiodothyronine; FT4=free thyroxine; HOMA=homeostasis model assessment. HOMA index was calculated by the following formula: [insulin (μU/mL)*glycaemia (mg/dL)]/405. Data underlined are the median (min-max) of the total number of cases. Data between round brackets are mean values±SD. a, b, c, d, and e indicate, respectively, young adults, adults, older adults, nonagenarians, and centenarians. The table shows the Pairwise comparisons between the different groups, i.e., a, b, c, d, and e stratified for gender. p-value≤0.05 is considered significant; ns=not significant.