Table 6.
Hematochemical parameters: Liver parameters.
| Variable (unit of measurement) |
(a) Young Adults (18-39 y.o.) N=29; M=13; W=16 |
(b) Adults (40-64 y.o.) N=40; M=21; W=19 |
(c) Older adults (65-89 y.o.) N=54; M=28; W=26 |
(d) Nonagenarians (90-99) y.o. N=27; M=9; W=18 |
(e) Centenarians (100-111) y.o. N=23; M=6; W=17 |
Age | Interaction |
Gender |
|
|---|---|---|---|---|---|---|---|---|---|
| M | W | ||||||||
| ALT (U/L, <41) |
13.00 (7.00 -27.00) N=29, (14.48±5.42) M=13, (17.54±6.37) W=16, (12.00±2.78) |
17.00 (4.00 -72.00) N=40, (23.18±16.09) M=21, (29.76±19.31) W=19, (15.89±6.31) |
15.50 (7.00 -55.00) N=54, (18.54±10.02) M=28, (17.43±7.21) W=26, (19.73±12.41) |
11.00 (3.00 -33.00) N=27, (11.52±6.47) M=9, (13.67±7.92) W=18, (10.44±5.55) |
9.00 (5.00 -15.00) N=23, (9.74±2.77) M=6, (12.67±2.42) W=17, (8.70±2.08) |
(a vs b) (b vs d,e) (c vs e) |
(a vs b) (b vs c,d,e) |
(c vs e) | 0.03 |
| AST (U/L, <40) |
16.00 (12.00 -23.00) N=29, (16.17±2.93) M=13, (17.23±3.37) W=16, (15.31±2.27) |
17.00 (11.00 -35.00) N=40, (19.68±6.58) M=21, (21.57±6.79) W=19, (17.58±5.81) |
17.50 (11.00 -35.00) N=54, (19.85±10.03) M=28, (17.79±4.24) W=26, (22.08±13.56) |
15.00 (6.00 -33.00) N=27, (15.67±5.54) M=9, (15.00±4.80) W=18, (16.00±5.98) |
16.00 (10.00 -28.00) N=23, (17.61±4.62) M=6, (19.17±4.49) W=17, (17.06±4.67) |
ns | ns | ns | ns |
| GGT (U/L, 8-61) |
11.00 (5.00 -45.00) N=29, (14.07±9.47) M=13, (16.15±10.06) W=16, (12.38±8.92) |
17.50 (7.00 -112.00) N=40, (28.25±26.49) M=21, (36.67±28.56) W=19, (18.95±20.97) |
17.50 (7.00 -213.00) N=54, (26.09±33.23) M=28, (29.14±38.93) W=26, (22.81±8.96) |
10.00 (5.00 -43.00) N=27, (13.59±8.66) M=9, (15.00±8.37) W=18, (12.89±8.96) |
14.00 (6.00 -68.00) N=23, (16.78±14.88) M=6, (33.30±22.11) W=17, (10.94±3.53) |
ns | ns | ns | 0.01 |
| Bilirubin (mg/dL, <1.20) |
0.86 (0.28-2.33) N=29, (0.95±0.52) M=13, (1.08±0.57) W=16, (0.85±0.47) |
0.51 (0.26-2.40) N=40, (0.68±0.48) M=21, (0.83±0.56) W= 19, (0.51±0.32) |
0.52 (0.17-1.71) N=54, (0.53±0.25) M=28, (0.63±0.29) W=26, (0.43±0.14) |
0.44 (0.16-0.95) N=27, (0.46±0.20) M=9, (0.49±0.20) W=18, (0.44±0.20) |
0.40 (0.20-1.78) N=23, (0.55±0.40) M=6, (0.91 0.65) W=17, (0.43±0.15) |
(a vs b,c,d) | ns | ns | <0.001 |
| Conjugated bilirubin (mg/dL, <0.30) |
0.35 (0.16-0.65) N=29, (0.36±0.13) M=13, (0.39±0.13) W=16, (0.33±0.13) |
0.22 (0.12-0.62) N=40, (0.25±0.12) M=21, (0.29±0.12) W=19, (0.21±0.10) |
0.21 (0.11-0.49) N=54, (0.23±0.08) M=28, (0.26±0.09) W=26, (0.18±0.05) |
0.20 (0.10-0.45) N=27, (0.21±0.08) M=9, (0.23±0.10) W=18, (0.20±0.07) |
0.19 (0.12-0.95) N=23, (0.24±0.18) M=6, (0.41±0.29) W=17, (0.18±0.04) |
(a vs b,c,d) | (a vs c,d) | (a vs b,c,d,e) | <0.001 |
| Albumin (g/L, 38-48) | 46.05 (33.90-54.40) N=28, (46.13±3.81) M=12, (48.06±3.02) W=16, (44.68±3.77) |
45.30 (40.40-50.60) N=39, (45.42±2.92) M=21, (46.48±2.47) W=18, (44.18±2.98) |
43.00 (38.40-51.60) N=53, (43.45±2.84) M=28, (43.96±3.06) W=26, (42.88±2.50) |
39.10 (34.20-47.50) N=27, (39.66 3.48) M=9, (40.18±3.53) W=18, (39.40±3.53) |
39.30 (31.10-46.40) N=22, (39.02±3.92) M=5, (40.16±2.73) W=17, (38.69±4.22) |
(a vs c,d,e) (b vs d,e) (c vs d,e) |
ns | ns | <0.001 |
| Total proteins (g/L, 66-87) |
71.50 (59.90-82.20) N=29, (71.52±5.78) M=13, (73.01±4.58) W=16, (70.31±6.50) |
69.95 (59.60-82.00) N=40, (69.75±4.54) M=21, (69.93±2.62) W=19, (69.55±6.09) |
68.10 (60.50-78.10) N=54, (68.32±4.25) M=28, (68.19±4.37) W=26, (68.46±4.20) |
67.70 (54.30-79.00) N=27, (68.01±5.48) M=9, (68.47±3.94) W=18, (67.78±6.21) |
67.00 (58.50-80.00) N=23, (66.73±5.28) M=6, (67.10±6.56) W=17, (66.61±4.98) |
(a vs c,e) | ns | ns | ns |
Abbreviations: y.o.=years old; N=total number of cases; M=men; W=women; SD=standard deviation; ALT=alanine transaminase; AST=aspartate transaminase; GGT=gamma-glutamil transferase. Data underlined are the median (min-max) of the total number of cases. Data between round brackets are mean values±SD. a, b, c, d, and e indicate, respectively, young adults, adults, older adults, nonagenarians, and centenarians. The table shows the Pairwise comparisons between the different groups, i.e., a, b, c, d, and e stratified for gender. p-value≤0.05 is considered significant; ns=not significant.