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. 2021 Sep 16;2021:7319417. doi: 10.1155/2021/7319417

Table 5.

Effect of Xuefu Zhuyu decoction on depressive symptoms and serum levels of depression-related factors in coronary heart disease patients (x ± SD).

Placebo Xuefu Zhuyu P value NDp Dp
Placebo Xuefu Zhuyu P value Placebo Xuefu Zhuyu P value
n 13 17
15 15 7 6 8 9

HDRS scores Baseline 7.67 ± 3.46 10.73 ± 5.17 0.442 4.71 ± 1.38 5.83 ± 2.40 0.697 10.25 ± 2.43 14.00 ± 3.64 0.212
Treatment 5.63 ± 3.01 5.13 ± 3.52 0.861 3.80 ± 1.30 3.83 ± 3.13 0.989 6.29 ± 3.77 6.00 ± 3.67 0.929
P value 0.132 0.002 0.274 0.242 0.029 0.000 ∗∗

Serotonin Baseline 11.58 ± 3.97 10.41 ± 1.90 0.669 13.59 ± 3.87 11.05 ± 1.93 0.367 11.09 ± 4.21 10.01 ± 1.89 0.505
Treatment 12.69 ± 2.95 12.40 ± 2.48 0.903 10.59 ± 1.12 11.24 ± 1.78 0.621 13.89 ± 3.04 13.12 ± 2.68 0.759
P value 0.463 0.031 0.191 0.872 0.182 0.018

BDNF Baseline 378.55 ± 118.75 357.25 ± 96.48 0.821 328.07 ± 155.19 377.69 ± 111.53 0.676 407.40 ± 93.74 344.47 ± 91.46 0.452
Treatment 443.52 ± 99.95 431.50 ± 166.34 0.920 454.84 ± 113.64 485.83 ± 175.90 0.810 437.06 ± 100.31 397.54 ± 162.26 0.738
P value 0.180 0.177 0.236 0.279 0.578 0.434

P < 0.05 and ∗∗P < 0.001 versus baseline.