Table 5.
Placebo | Xuefu Zhuyu | P value | NDp | Dp | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Placebo | Xuefu Zhuyu | P value | Placebo | Xuefu Zhuyu | P value | |||||
n | 13 | 17 | ||||||||
15 | 15 | 7 | 6 | 8 | 9 | |||||
| ||||||||||
HDRS scores | Baseline | 7.67 ± 3.46 | 10.73 ± 5.17 | 0.442 | 4.71 ± 1.38 | 5.83 ± 2.40 | 0.697 | 10.25 ± 2.43 | 14.00 ± 3.64 | 0.212 |
Treatment | 5.63 ± 3.01 | 5.13 ± 3.52 | 0.861 | 3.80 ± 1.30 | 3.83 ± 3.13 | 0.989 | 6.29 ± 3.77 | 6.00 ± 3.67 | 0.929 | |
P value | 0.132 | 0.002 ∗ | 0.274 | 0.242 | 0.029 ∗ | 0.000 ∗∗ | ||||
| ||||||||||
Serotonin | Baseline | 11.58 ± 3.97 | 10.41 ± 1.90 | 0.669 | 13.59 ± 3.87 | 11.05 ± 1.93 | 0.367 | 11.09 ± 4.21 | 10.01 ± 1.89 | 0.505 |
Treatment | 12.69 ± 2.95 | 12.40 ± 2.48 | 0.903 | 10.59 ± 1.12 | 11.24 ± 1.78 | 0.621 | 13.89 ± 3.04 | 13.12 ± 2.68 | 0.759 | |
P value | 0.463 | 0.031 ∗ | 0.191 | 0.872 | 0.182 | 0.018 ∗ | ||||
| ||||||||||
BDNF | Baseline | 378.55 ± 118.75 | 357.25 ± 96.48 | 0.821 | 328.07 ± 155.19 | 377.69 ± 111.53 | 0.676 | 407.40 ± 93.74 | 344.47 ± 91.46 | 0.452 |
Treatment | 443.52 ± 99.95 | 431.50 ± 166.34 | 0.920 | 454.84 ± 113.64 | 485.83 ± 175.90 | 0.810 | 437.06 ± 100.31 | 397.54 ± 162.26 | 0.738 | |
P value | 0.180 | 0.177 | 0.236 | 0.279 | 0.578 | 0.434 |
∗ P < 0.05 and ∗∗P < 0.001 versus baseline.