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. 2021 Sep 16;2021:5788602. doi: 10.1155/2021/5788602

Figure 1.

Figure 1

Schematic diagram of the experimental protocols (a) and assessments on neuroprotective and pyroptosis-inhibiting effects of TXL against cerebral I/R injuries (b–f). (b) Neurological deficits of successful MCAO/R rats with failure to extend right forepaw (white arrow) and circling to the right. (c) Neurological deficit scores of each group, n = 10. (d) Detection of LDH content, n = 4. (e) Representative pictures of PI immunofluorescent staining. The red dots represent the amount of nuclear PI uptake; scale bars, 50 μm. (f) Representative pictures of GSDMD-FL (yellow arrows) and GSDMD-N (red arrows) immunohistochemistry staining; scale bars, 50/20 μm. Data are presented as mean ± SEM. ∗∗P < 0.01 versus the sham group. P < 0.05 and ▲▲P < 0.01 versus the I/R group.