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Intervention effects of TXL on pyroptosis-related inflammatory responses after reperfusion. (a, c) Protein expression levels of NLRP3, caspase-1 p20, IL-1β, and IL-6 in each group. Data are presented as mean ± SEM. ∗∗P < 0.01 versus the sham group. ▲P < 0.05 and ▲▲P < 0.01 versus the I/R group. (b) Representative pictures of the double immunofluorescence staining of GFAP (green) and NLRP3 (red); scale bars, 20 μm.
