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. 2021 Sep 24;105(20):7635–7650. doi: 10.1007/s00253-021-11531-4

Fig. 1.

Fig. 1

Overview on potential sources of microorganisms in liquid nitrogen tanks storing organs, tissues, and cells of human, animals, plants, and microorganisms. The shading of the arrow (cell counts) shows the increase in the number of microbial cells with increasing storage time and number of openings which indicates the likelihood of consequences for human health and welfare if the material is contaminated (light: low, dark: high). 1Bajerski et al. 2020, 2Fountain et al. 1997, 3Ramin et al. 2014, 4Morris 2005, 5Molina et al. 2016, 6Knierim et al. 2017, 7Pessoa et al. 2014, 8Tedder et al. 1995, 9Bielanski et al. 2003, 10Vitrenko et al. 2017, 11Drexler and Uphoff 2002, 12Schafer et al. 1976. *Microoragnisms detected in LN tanks most probably originating from the stored material itself displayed in boxes with solid lines