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. 2021 Jul 30;40(38):5665–5676. doi: 10.1038/s41388-021-01952-w

Fig. 3. Cooperating genetic lesions contribute to AML1/ETO-driven leukemogenesis.

Fig. 3

Gene mutations conferring a positive prognostic impact are highlighted in green, while gene mutations with a poor prognostic are indicated in red. Gene mutations with an equivocal prognostic impact are shown in gray. The relative incidence of the respective mutation is depicted in percent. Mutations occurring more frequently in t(8;21) CBF-AML are portrayed to the left, while mutations with a preponderance in inv(16)/t(16;16) CBF-AML are portrayed to the right.