Fig. 2. Transcription differs between control human mast cell (HMC)-1 cells and imiquimod-treated HMC-1 cells. (A) A heatmap of hierarchical clustering indicates differentially expressed gene (rows) between control HMC-1 cells and imiquimod-treated HMC-1 cells (fold-change>2, p<0.05). Red indicates upregulation and blue indicates downregulation. (B) Functional enrichment analysis of highly regulated genes in control HMC-1 cells and imiquimod-treated HMC-1 cells were annotated in the GO category of biological process (left). Distribution of positively regulated genes was annotated in the GO category of biological process (right).
