Table 1. Oncogenic miRNA.
↑: increase; ↓: decrease: miR: microRNA, EMT: epithelial-mesenchymal transition
Copyright/License: Licensee MDPI, Basel, Switzerland. This figure is from an open-access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Adaptations were made to the original table.
Ingenito F, Roscigno G, Affinito A, Nuzzo S, Scognamiglio I, Quintavalle C, Condorelli G: The role of exo-miRNAs in cancer: a focus on therapeutic and diagnostic applications. Int J Mol Sci. 2019, 20:4687 [3].
Exosomal miRNA | Effect | Tumor |
miR-10b | Invasion ↑ | Breast cancer |
miR-32-5p | Drug resistance ↑ | Hepatocellular carcinoma |
miR-223 | Invasion ↑ | Pancreatic cancer |
miR-9 | Angiogenesis ↑ | Glioma |
miR-99a-5p, miR-125b-5p | Drug resistance ↑ | Large B-cell lymphoma |
miR-21, miR-378e, miR-143 | EMT and stemness ↑ | Breast cancer |
miR-93-5p | Growth ↑ | Esophageal cancer |