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. Author manuscript; available in PMC: 2022 Sep 23.
Published in final edited form as: Nat Prod Rep. 2021 Sep 23;38(9):1567–1588. doi: 10.1039/d1np00007a

Figure 13:

Figure 13:

Biosynthetic mechanism for assembly of the hapalindole and fischerindole cores based on independent studies of Sherman64 and Liu.61 Cis-indole isonitrile core (1) is highlighted in blue. GPP is highlighted in red.