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. Author manuscript; available in PMC: 2022 Sep 23.
Published in final edited form as: Nat Prod Rep. 2021 Sep 23;38(9):1567–1588. doi: 10.1039/d1np00007a

Figure 15:

Figure 15:

Crystal structure of dimeric interface of HpiC1 reported in Newmister et al.76 and supported by functional data in Li et al.68 Dimeric interface is highlighted by the blue cavity. Red brackets encompass the combined active site while green brackets encompass the active site from the individual Stig cyclase monomers. Blue cavity calculated using CAVER software.90