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. Author manuscript; available in PMC: 2022 Sep 23.
Published in final edited form as: Nat Prod Rep. 2021 Sep 23;38(9):1567–1588. doi: 10.1039/d1np00007a

Figure 21:

Figure 21:

Left: Crystal structure of WelO5 with 36 obtained by Mitchell et al.84 Right: Structure of active site with key residues highlighted. His164 and His259 coordinate to Fe(II) (orange sphere). Ala82 and Met225 hydrogen bond to 36 for proper configuration. Ser189 coordinates the chloride ion (green sphere).