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. 2021 Sep 23;11:18995. doi: 10.1038/s41598-021-98484-w

Table 2.

Comparison between findings at baseline and 6 months after ablation.

Baseline 6 M p
MRI findings
DWI positive patients, n (%) 63 (87.5) 0 (0) Not applicable
DWI positive lesions, n 421 0
 Cortical 361 0
 Subcortical, deep 60 0
DIR positive patients, n (%) 62 (86.1) 21 (29.2)
DIR positive lesions, n 362 35
 Cortical 307 18
 Subcortical, deep 55 17
Neuropsychological test Normal range Baseline 6 M p
MMSE ≧ 24 27.9 ± 2.39 28.5 ± 1.98 0.037*
RCPM Age dependent 31.4 ± 4.0 31.8 ± 3.1 0.503
RCPM time (s) Age dependent 391 ± 92.2 392 ± 116 0.69
RBMT immediate recall Age dependent 10.1 ± 3.4 14.3 ± 4.2  < 0.001*
RBMT delayed recall Age dependent 7.8 ± 2.98 13.1 ± 4.0  < 0.001*
Necker’s cube 2.3 ± 0.5 2.4 ± 0.6 0.157
MCAS  ≤ 2 2.4 ± 1.4 1.8 ± 1.3  < 0.001*
TMT-A Age dependent 105 ± 31.2 97.8 ± 37.1 0.09
TMT-B Age dependent 160.2 ± 146 141.1 ± 61.2 0.098
Word fluency (vegetable) 15.3 ± 12.7 13.5 ± 4 0.436
Word fluency (animal) 16.2 ± 4.7 16.9 ± 4.6 0.228
Word fluency (letter) 6.5 ± 1.7 6.7 ± 1.9 0.17
Cardiac function Normal range Baseline 3–6 M
EF (%) 50–80 64.5 ± 7.2 67.2 ± 7.7 0.025*
LAVI (ml/m2)  < 34 46.8 ± 16.9 40.9 ± 13.5 0.002*
BNP (pg/ml) 0–8.4 89.1 ± 70.9 62.5 ± 70.1 0.001*

DWI Diffusion-weighted imaging, DIR Double inversion recovery, MCAS Mie constructional apraxia scale, EF Ejection fraction, LAVI Left atrial volume index, BNP Brain natriuretic peptide.