Table 2.
Concordance analysis per embryo.
| Ion S5 | Miseq | |
|---|---|---|
| Number of embryos tested | 107 | 107 |
| Number of embryos screened by NGS | 107 | 107 |
| Number of embryos with conclusive result a | 104 | 104 |
| Number of embryos with inconclusive result | 3 | 3 |
| Number of embryos with aneuploid calling b | 54 | 55 |
| Ploidy conclusion | ||
| Euploid | 50 (48.0%) | 49 (47.1%) |
| Low-rate mosaic (20–50% aneuploidy) | 6 (5.8%) | 11 (10.6%) |
| High-rate mosaic (50–80% aneuploidy) | 8 (7.7%) | 9 (8.7%) |
| Aneuploid | 40 (38.5%) | 35 (33.6%) |
| Single-chromosome aneuploidy | 28 | 24 |
| Double-chromosome aneuploidy | 5 | 3 |
| Multiple aneuploidy c | 7 | 8 |
| Number of concordant embryos d | 103 | |
| Number of non-concordant embryos e | 1 | |
| Concordance per embryo | 99.04% | |
aIt excludes embryos with chaotic patterns that the ploidy could not be interpreted.
bIt includes embryos with mosaicism and aneuploidy.
cIt includes embryos with more than two aneuploid chromosome pairs.
dIt includes embryos identified as euploid or mosaic/aneuploid on the both two NGS systems.
eEmbryos identified as euploid on only one NGS system, and as mosaic or aneuploid on the other system.