Table 3.
Concordance analysis per chromosome pair.
| Ion S5 | Miseq | |
|---|---|---|
| Total chromosome pairs | 2392 | 2392 |
| Chromosomes with conclusive result a | 2277 | 2277 |
| Chromosomes with inconclusive result | 115 | 115 |
| Chromosomes with aneuploid calling b | 107 | 95 |
| Chromosome category | ||
| Diploid | 2170 (95.3%) | 2182 (95.8%) |
| Low-rate mosaic (20–50%) | 27 (1.2%) | 22 (1.0%) |
| High-rate mosaic (50–80%) | 15 (0.7%) | 15 (0.7%) |
| Aneuploid | 65 (2.8%) | 58 (2.5%) |
| Overall concordant chromosome pairs c | 2265 | |
| Overall non-concordant chromosome pairs d | 12 | |
| Concordance rate per chromosome pair | 99.47% | |
aIt excludes embryos with chaotic mosaicism, in which the individual chromosomes affected could not be distinguished.
bIt includes individual chromosome pairs with mosaicism or aneuploidy.
cChromosome pairs identified as diploid or mosaic/aneuploid on the both two NGS systems. Mosaic/aneuploid chromosome pairs with different aneuploid percentages on each system are also included.
dChromosome pairs identified as diploid on the only one system, and as mosaic/aneuploid on the other system.