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. 2021 Sep 23;11:18931. doi: 10.1038/s41598-021-98318-9

Table 3.

Concordance analysis per chromosome pair.

Ion S5 Miseq
Total chromosome pairs 2392 2392
Chromosomes with conclusive result a 2277 2277
Chromosomes with inconclusive result 115 115
Chromosomes with aneuploid calling b 107 95
Chromosome category
 Diploid 2170 (95.3%) 2182 (95.8%)
 Low-rate mosaic (20–50%) 27 (1.2%) 22 (1.0%)
 High-rate mosaic (50–80%) 15 (0.7%) 15 (0.7%)
 Aneuploid 65 (2.8%) 58 (2.5%)
Overall concordant chromosome pairs c 2265
Overall non-concordant chromosome pairs d 12
Concordance rate per chromosome pair 99.47%

aIt excludes embryos with chaotic mosaicism, in which the individual chromosomes affected could not be distinguished.

bIt includes individual chromosome pairs with mosaicism or aneuploidy.

cChromosome pairs identified as diploid or mosaic/aneuploid on the both two NGS systems. Mosaic/aneuploid chromosome pairs with different aneuploid percentages on each system are also included.

dChromosome pairs identified as diploid on the only one system, and as mosaic/aneuploid on the other system.