Table 3.
The efficacy of AGEage ≥ 43.2 in early identifying LEAD in type 2 diabetic patients.
| AUC | Sensitivity | Specificity | PPV | NPV | |
|---|---|---|---|---|---|
| Total | 0.731 (0.703–0.758) | 75.5 (71.6–79.2) | 59.3 (54.9–63.6) | 65.0 (62.3–67.6) | 70.8 (67.1–74.1) |
| Sex | |||||
| Male | 0.768 (0.732–0.801) | 73.8 (68.7–78.5) | 68.5 (62.6–74.0) | 73.6 (69.8–77.1) | 68.8 (64.3–72.9) |
| Female | 0.696 (0.650–0.740) | 78.6 (71.9–84.3) | 48.5 (41.9–55.1) | 54.4 (50.7–58.0) | 74.3 (68.0–79.8) |
| BMI | |||||
| <25 | 0.750 (0.712–0.785) | 82.1 (77.1–86.4) | 56.8 (50.9–62.7) | 65.2 (61.8–68.4) | 76.4 (71.2–80.9) |
| ≥25 | 0.715 (0.670–0.756) | 67.4 (60.9–73.5) | 62.4 (55.7–68.8) | 64.8 (60.3–69.1) | 65.1 (60.1–69.8) |
| Diabetes family history | |||||
| Yes | 0.721 (0.683–0.756) | 77.0 (71.9–81.6) | 55.2 (49.3–60.9) | 63.5 (60.2–66.7) | 70.3 (65.3–74.9) |
| No | 0.748 (0.702–0.789) | 73.3 (66.6–79.2) | 65.4 (58.4–71.9) | 67.6 (62.9–71.9) | 71.3 (65.9–76.1) |
| Current smoker | |||||
| Yes | 0.711 (0.650–0.767) | 70.1 (61.7–77.6) | 66.7 (56.9–75.4) | 72.7 (66.7–78.1) | 63.7 (56.8–70.1) |
| No | 0.744 (0.711–0.774) | 77.6 (73.0–81.7) | 57.3 (52.3–62.2) | 62.8 (59.8–65.7) | 73.3 (69.1–77.2) |
NPV, negative predictive value; PPV, positive predictive value.