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Clinician vs. patient-based alerts (subgroup analysis). Outcomes shown are HF or CV hospitalizations. There was an increase in both CV or HF hospitalizations and HF hospitalizations alone when studies used devices with patient alerts (RR 1.55 [95% CI 1.28–1.89]) compared to clinician alerts (RR 0.91 [95% CI 0.76–1.09]) and test for subgroup differences: I2 = 93.7%, chi2 = 15.87, p < 0.0001
