Table 4.
Neonatal outcomes in singleton birth after frozen-thawed embryo transfer in the absence (0 CL) or presence (≥1 CL) of a corpus luteuma.
| Outcomes | 0 CL | ≥1 CL | P-value | Crude OR (95% CI) | P-value | Adjusted ORg | P-value |
|---|---|---|---|---|---|---|---|
| (n = 114) | (n = 68) | (95% CI) | |||||
| Gestational age, days | 277.0 ± 19b | 276.5 ± 16 | 0.63 | NA | NA | NA | NA |
| Gender | NA | NA | NA | NA | |||
| - Male | 61 (53.5)b | 38 (55.9)d | 0.72 | ||||
| - Female | 52 (45.6) | 29 (42.6) | |||||
| Preterm birth (<37 weeks) | 14 (12.3) | 7 (10.3) | 0.67 | 1.23 (0.47 – 3.22) | 0.67 | 1.07 (0.38 – 3.04) | 0.90 |
| Very preterm birth (<32 weeks) | 1 (0.9) | 0 (0.0) | 1.0 | NA | NA | NA | NA |
| Birthweight, g | 3,510.0 ± 608b | 3327.5 ± 735 | 0.03 | NA | NA | NA | NA |
| Birthweight percentile (<1 - >99) | 51.5 ± 41e | 42.5 ± 42 | 0.02 | NA | NA | NA | NA |
| Birthweight, g (male) | 3,532.5 ± 69.8 | 3,430.0 +/- 685.0 | 0.45 | NA | NA | NA | NA |
| Birthweight percentile (<1 - >99) (male) | 47.5 ± 40.0 | 47.5 ± 45.0 | 0.58 | NA | NA | NA | NA |
| Birthweight, g (female) | 3402.3 ± 465.4# | 3154.0 ± 440.9# | 0.02 | NA | NA | NA | NA |
| Birthweight percentile (<1 - >99) (female) | 57.4 ± 40 | 37.0 ± 32 | 0.007 | NA | NA | NA | NA |
| Birthweight category | |||||||
| Low birthweight (<2,500 g) | 9 (7.9) | 4 (5.9) | 0.77 | 1.39 (0.41 – 4.68) | 0.60 | 1.28 (0.33 – 4.91) | 0.72 |
| Very low birthweight (<1,500 g) | 2 (1.8) | 0 (0.0) | 0.53 | NA | NA | NA | NA |
| Macrosomia (>4,000 g) | 17 (14.9) | 8 (11.8) | 0.54 | 1.33 (0.54 – 3.27) | 0.54 | 1.42 (0.55 – 3.70) | 0.47 |
| SGA (<10 percentile) | 8 (7.0) | 10 (14.7) | 0.10 | 0.44 (0.17 – 1.18) | 0.10 | 0.41 (0.14 – 1.23) | 0.11 |
| LGA (>90 percentile) | 11 (9.6) | 7 (10.3) | 0.92 | 0.95 (0.35 – 2.58) | 0.92 | 1.00 (0.36 – 2.77) | >0.9 |
| Body size newborn - cm | 52 ± 3c | 51 ± 4d | 0.06 | NA | NA | NA | NA |
| Head circumference - cm | 35.5 ± 2c | 35.0 ± 2d | 0.07 | NA | NA | NA | NA |
| APGAR <7 at 5 min | 2 (1.8) | 0 (0.0) | 0.53 | NA | NA | NA | NA |
| Neonatal morbidityf | 8 (7.0) | 8 (11.8) | 0.28 | 0.57 (0.20 – 1.60) | 0.29 | 0.19 (0.16 – 1.44) | 0.19 |
| Admission to ICU or NICU | 16 (14.0) | 16 (23.5) | 0.12 | 0.54 (0.25 – 1.17) | 0.12 | 0.49 (0.22 – 1.09) | 0.08 |
| Major birth defects | 4 (3.5) | 3 (4.4) | 0.75 | 0.78 (0.17 – 3.61) | 0.75 | 0.63 (0.13 – 3.15) | 0.59 |
Data are presented as median ± interquartile range or as number (% of total).
113/114 outcomes available.
111/114 outcomes available.
67/68 outcomes available.
112/114 outcomes available.
Icterus, infection, sepsis, infant respiratory distress syndrome, hypoglycemia.
Adjustments were made for the following confounders: child's sex, nulliparity, HDP, placenta-associated complications, smoking during pregnancy, gestational diabetes.
CI, confidence interval; CL, corpus luteum; ICU, intermediate care unit; LGA, large for gestational age; NICU, intensive care unit; OR, odds ratio; SGA, small for gestational age.
Means that this value is a mean +/− standard devation instead of a median value.