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The molecular simulation between five anthraquinones and SIRT1 (PDB code: 4I5I). (A-E) Rhein, emodin, aloe-emodin, chrysophanol, and physcion in the active site of SIRT1. (F-J) The binding modes of the five ligands with receptor SIRT1. Green dotted line: H-bonds; red arc: hydrophobic interaction.
