TABLE 6.

Effect of PNMS, genotype and gene-by-environment interaction on HCV/TIC volume in girls, controlling for socioeconomic status With left HCV/TIV.

	Left HCV/TIV ratio (Girls)										Right HCV/TIV ratio (Girls)
	Objective PNMS			Genotype			Interaction			Total	Objective PNMS			Genotype			Interaction			Total
	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2
COMT
AA vs. AG vs. GG				−0.055	0.003	0.777	−0.467	0.020	0.468	0.233				−0.227	0.051	0.235	−0.623	0.036	0.320	0.241
AA + AG vs. GG	0.106	0.008	0.628	0.002	0.000	0.991	0.653	0.014	0.544	0.224	0.392	0.154	0.048	0.122	0.015	0.529	0.791	0.021	0.462	0.189
AA vs. AG + GG				−0.084	0.007	0.664	−0.527	0.020	0.461	0.237				−0.260	0.066	0.177	−0.816	0.049	0.235	0.269
	Subjective PNMS			Genotype			Interaction			Total	Subjective PNMS			Genotype			Interaction			Total
	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2
COMT
AA vs. AG vs. GG				−0.058	0.003	0.769	−1.211	0.144	0.047	0.358				−0.220	0.048	0.261	−1.091	0.117	0.070	0.327
AA + AG vs. GG	0.031	0.001	0.879	0.009	0.000	0.966	3.271	0.330	0.001	0.541	−0.098	0.009	0.628	0.108	0.011	0.591	2.785	0.244	0.007	0.418
AA vs. AG + GG				−0.084	0.007	0.671	−0.640	0.035	0.347	0.252				−0.260	0.066	0.185	−0.738	0.047	0.257	0.275
	Cognitive appraisal			Genotype			Interaction			Total	Cognitive appraisal			Genotype			Interaction			Total
	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2	BETA	CH R2	p	BETA	CH R2	p	BETA	CH R2	p	R 2
COMT
AA vs. AG vs. GG				−0.090	0.008	0.637	0.335	0.009	0.618	0.286				−0.247	0.059	0.209	0.739	0.045	0.270	0.268
AA + AG vs. GG	0.255	0.059	0.197	0.061	0.003	0.759	−0.120	0.000	0.916	0.272	0.104	0.010	0.608	0.154	0.022	0.444	0.124	0.000	0.915	0.186
AA vs. AG + GG				−0.095	0.009	0.621	0.414	0.012	0.573	0.289				−0.264	0.068	0.178	1.062	0.077	0.141	0.308

CH R², Change in R-squared (R²).

COMT genotype coding:

AA (1) vs. AG (2) vs. GG (3);

AA (1) vs. AG + GG (2);

GG (1) vs. AA + AG (2);

Bold means significant.