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. 2021 Sep 23;9(18):e15029. doi: 10.14814/phy2.15029

FIGURE 1.

FIGURE 1

Schematic representation of the tripartite synapse. Left: astrocytes (green) are in close contact with blood vessels and synapses. Inset: in addition to postsynaptic receptors, neurotransmitters activate receptors expressed by astrocyte. This induces an increase in intracellular Ca2+ concentration, which triggers the release of gliotransmitters that interact with pre‐ and postsynaptic receptors