TABLE 2.
Species | Contaminant | Biomarker | Effect | References |
C. virginica | WAF of PAHs in sediment | Infection | Increased prevalence of Perkinsus infection | Chu and Hale. 1994 |
C. virginica | PAHs + heavy metals + pesticides in sediment suspension | Histology | Extensive neoplasia Renal cell tumors, Gill filament tumors, Gastrointestinal adenocarcinoma Neuroblastoma, Circulatory system tumors, Gonadal papillary lesions | Gardner et al., 1991 |
M. gigas | PAHs + heavy metals + miscellaneous contaminants in sediment or elutriate | Gamete health Fertilization Embryogenesis | No change in fertilization rate, Larval abnormalities | Geffard et al., 2001 |
M. gigas | PAH Heavy metals PAHs + heavy metals miscellaneous contaminants elutriate, contaminated algae | Embryogenesis Larval growth | Larval abnormalities, Mortality, Delayed larval growth | Geffard et al., 2002 |
M. gigas | PAHs + heavy metals (Cd, Cu, Zn) + miscellaneous contaminants in sediment or elutriate | Larval growth Metallothionein | Larval abnormalities, Metallothionein produced | Geffard et al., 2003 |
M. gigas | PAHs (various) + heavy metals (Cd, Cu, Zn) + miscellaneous contaminants in sediment or elutriate | Embryogenesis Larval growth | Delayed blastula formation, Larval abnormalities | Geffard et al., 2004 |
C. virginica | PAHs + heavy metals + miscellaneous contaminants in sediment suspension | Infection Immune function | No significant difference in neutral red uptake by hemocytes, Increased tetrazolium dye reduction, Increased 3H-leucine incorporation, Significantly increased rate of Perkinsus infection | Chu et al., 2002 |
C. virginica | PAHs + miscellaneous contaminants in sediment | Embryogenesis Larval development | Fertilization inhibition, Embryo abnormalities, Reduction in shell growth | Boulais et al., 2018 |
C. brasiliana | PAHs + heavy metals + miscellaneous chemicals in coal tar-based paint | Lysosomes | Lysosomal destabilization | Chiovatto et al., 2021 |
The contaminant mixtures are either derived from sediments collected from contaminated sites or from anthropogenic chemical products. This non-exhaustive list provides a collection of common end points used to study chemical toxicity and some of the effects of the contaminants that may manifest in a less controlled setting.