Table 2.
Variable | Group | TLVsupine | OLVsupine | OLVsemilateral | OLVlateral | OLVprone | Sequence P = | Group P = | Position P = | ME P = | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Center of perfusion left-right axis [% from left] | Normo | 30.7 ± 5.0 | p | 28.8 ± 3.6 | se, l, p | 31.6 ± 2.6 | p | 31.1 ± 4.2 | p | 32.8 ± 2.6 | 0.614 | 0.695 | ≤ 0.001 | 0.368 | |
Hypo | 28.5 ± 4.9 | 29.0 ± 3.3 | 29.9 ± 3.5 | 30.8 ± 3.1 | 33.4 ± 2.7 | ||||||||||
Center of perfusion dorsal-ventral axis [% from dorsal] | Normo Hypo |
27.5 ± 3.6 27.5 ± 4.4 |
28.9 ± 3.0 28.3 ± 3.9 |
sl, l, p | 27.1 ± 3.1 27.7 ± 4.1 |
27.3 ± 2.9 27.5 ± 3.3 |
27.5 ± 3.0 27.7 ± 3.8 |
0.673 | 0.948 | 0.025 | 0.627 | ||||
Center of perfusion caudal-cranial axis [% from caudal] | Normo Hypo |
45.4 ± 6.0 42.9 ± 3.7 |
sl | 46.0 ± 5.2 44.2 ± 4.1 |
46.8 ± 4.6 46.1 ± 4.5 |
46.1 ± 4.7 45.0 ± 4.0 |
45.2 ± 3.1 45.3 ± 3.5 |
0127 | 0.462 | 0.048 | 0.444 | ||||
CV of relative perfusion % | Normo | 157.9 ± 19.1 | sl, l, p | 154.4 ± 11.2 | 151.4 ± 15.9 | 147.2 ± 10.3 | 139.4 ± 10.4 | s, se | 0.026 | 0.075 | ≤ 0.001 | 0.104 | |||
Hypo | 180.0 ± 24.3 | 153.4 ± 14.7 | 152.9 ± 14.9 | 145.4 ± 8.4 | 143.8 ± 8.0 |
Mean ± SD; Normo, normovolemia group; Hypo, hypovolemia group; TLV, two-lung ventilation; OLV, one-lung ventilation; CV, coefficient of variation; ME, mixed effects position × group. Significance was accepted at P < 0.05. The differences between the two groups, respective body positions, and the sequences of interventions were compared using a linear mixed-effects model with repeated measures, with TLVsupine, OLVsupine, OLVsemilateral, OLVlateral, and OLVprone as within-subject factors and with group and sequence as fixed between subject-factors. The significance of the within-subject factors was corrected for sphericity according to Greenhouse–Geisser. Pairwise post-hoc multiple comparisons were performed according to least significant difference (LSD) when appropriate. s P < 0.05 vs. OLVsupine, se P < 0.05 vs. OLVsemilateral, l P < 0.05 vs. OLVlateral, and p P < 0.05 vs. OLVprone.