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. 2021 Sep 10;12:717269. doi: 10.3389/fphys.2021.717269

Table 2.

Perfusion of the left lung.

Variable Group TLVsupine OLVsupine OLVsemilateral OLVlateral OLVprone Sequence P = Group P = Position P = ME P =
Center of perfusion left-right axis [% from left] Normo 30.7 ± 5.0 p 28.8 ± 3.6 se, l, p 31.6 ± 2.6 p 31.1 ± 4.2 p 32.8 ± 2.6 0.614 0.695 ≤ 0.001 0.368
Hypo 28.5 ± 4.9 29.0 ± 3.3 29.9 ± 3.5 30.8 ± 3.1 33.4 ± 2.7
Center of perfusion dorsal-ventral axis [% from dorsal] Normo
Hypo
27.5 ± 3.6
27.5 ± 4.4
28.9 ± 3.0
28.3 ± 3.9
sl, l, p 27.1 ± 3.1
27.7 ± 4.1
27.3 ± 2.9
27.5 ± 3.3
27.5 ± 3.0
27.7 ± 3.8
0.673 0.948 0.025 0.627
Center of perfusion caudal-cranial axis [% from caudal] Normo
Hypo
45.4 ± 6.0
42.9 ± 3.7
sl 46.0 ± 5.2
44.2 ± 4.1
46.8 ± 4.6
46.1 ± 4.5
46.1 ± 4.7
45.0 ± 4.0
45.2 ± 3.1
45.3 ± 3.5
0127 0.462 0.048 0.444
CV of relative perfusion % Normo 157.9 ± 19.1 sl, l, p 154.4 ± 11.2 151.4 ± 15.9 147.2 ± 10.3 139.4 ± 10.4 s, se 0.026 0.075 ≤ 0.001 0.104
Hypo 180.0 ± 24.3 153.4 ± 14.7 152.9 ± 14.9 145.4 ± 8.4 143.8 ± 8.0

Mean ± SD; Normo, normovolemia group; Hypo, hypovolemia group; TLV, two-lung ventilation; OLV, one-lung ventilation; CV, coefficient of variation; ME, mixed effects position × group. Significance was accepted at P < 0.05. The differences between the two groups, respective body positions, and the sequences of interventions were compared using a linear mixed-effects model with repeated measures, with TLVsupine, OLVsupine, OLVsemilateral, OLVlateral, and OLVprone as within-subject factors and with group and sequence as fixed between subject-factors. The significance of the within-subject factors was corrected for sphericity according to Greenhouse–Geisser. Pairwise post-hoc multiple comparisons were performed according to least significant difference (LSD) when appropriate. s P < 0.05 vs. OLVsupine, se P < 0.05 vs. OLVsemilateral, l P < 0.05 vs. OLVlateral, and p P < 0.05 vs. OLVprone.