Table 2.
Clinical characteristics of patients with RR-MS according to the age group.
| “Younger” | “Older” | B–H adjusted p | ||
|---|---|---|---|---|
| Patients | N | 133 | 133 | |
| Age at onset, years | Median (IQR) | 25.5 (21.68–29.39) | 42.49 (37.82–49.29) | – |
| Sex, F | N (%) | 89 (66.9) | 94 (70.7) | 0.508* |
| Disease duration, months | Median (IQR) | 3 (0.97–16.95) | 10.7 (1.96–36.25) | 0.007# |
| Unique CSF OCB, present | N (%) | 98/130 (75.4) | 92/131 (70.2) | 0.407* |
| EDSS | Median (IQR) | 1.5 (1–2) | 2 (1–2.5) | 0.281# |
| Clinical disease activity, yes | N (%) | 63/132 (47.7) | 31/131 (23.7) | <0.001* |
| Radiological disease activity, yes | N (%) | 66/128 (51.6) | 42/124 (33.9) | 0.009* |
| BREMS at onset | Median (IQR) | −0.03 (−0.6 to 0.47) | 0.12 (−0.5 to 0.89) | <0.001# |
*
p-value of the χ2 test;
#
p-value of the Mann–Whitney U test.
B–H, Benjamini–Hochberg; BREMSO, Bayesian risk estimate for MS at onset; CSF, cerebrospinal fluid; EDSS, Expanded Disability Status Scale; MS, multiple sclerosis; OCB, oligoclonal bands; RR, relapsing-remitting.