Table 1.
Population clinical characteristics of total acute ischemic stroke patients from the MRI-GENIE study and those included the analysis with available admission NIHSS, 3- to 6-month mRS scores and WMHv, and the low, expected, and excessive uWMH burden groups.
| Total (n = 5,822) | Total included in the analysis (n = 890) | Low (n = 140) | Expected (n = 599) | Excessive (n = 151) | |
|---|---|---|---|---|---|
| Age, average (SD) | 61.3 (15.2) | 63.7 (15.0) | 61.6 (14.1) | 64.1 (15.5) | 64.2 (13.9) |
| Sex, n (%) | 2,416 (41.5%) | 379 (42.6%) | 59 (42.1%) | 251 (41.9%) | 69 (45.7%) |
| HTN, n (%) | 3,849 (66.1%) | 541 (60.8%) | 88 (62.9%) | 355 (59.3%) | 98 (64.9%) |
| DM, n (%) | 1,480 (25.4%) | 180 (20.2%) | 24 (17.1%) | 131 (21.9%) | 25 (16.6%) |
| AF, n (%) | 741 (12.7%) | 140 (15.7%) | 19 (13.6%) | 98 (16.4%) | 23 (15.2%) |
| CAD, n (%) | 1,021 (17.5%) | 140 (15.7%) | 13 (9.3%) | 105 (17.5%) | 22 (14.6%) |
| SMK, n (%) | 3,342 (57.4%) | 475 (53.4%) | 70 (50.0%) | 331 (55.3%) | 74 (49.0%) |
| PS, n (%) | 749 (12.9%) | 85 (9.6%) | 13 (9.3%) | 59 (9.8%) | 13 (8.6%) |
| NIHSS, median (IQR) | N/A | 3 (5) | 3 (4) | 3 (6) | 3 (5) |
| uWMH, avg (std) | N/A | 0 (1.1) | −1.8 (0.5) | 0.0 (0.6) | 1.6 (0.4) |