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. 2021 Sep 10;12:700616. doi: 10.3389/fneur.2021.700616

Table 5.

Acute stroke severity subgroup analysis.

Acute stroke severity group Excessive/
low
Excessive/
expected
Expected/
low
Mild (n = 666) OR 0.45 0.58 0.76
p, 95% CI <0.01 (0.26, 0.78) 0.01 (0.38, 0.89) 0.25 (0.48, 1.21)
Severe (n = 224) OR 0.23 0.57 0.40
p, 95% CI <0.01 (0.08, 0.65) 0.21 (0.23, 1.39) 0.02 (0.18, 0.86)

The odds ratios of patients who achieved full functional independence (mRS excellent: mRS scores 0–1) of the excessive uWMH burden groups to the low (excessive/low) and expected (excessive/expected) groups and of the expected group to the low (expected/low) group in the mild acute stroke severity group (mild, NIHSS < 7) and the severe acute stroke severity group (severe, NIHSS ≥ 7).