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. 2021 Sep 10;11:725922. doi: 10.3389/fonc.2021.725922

Table 1.

>Statistical analysis results of clinical characteristics.

Characteristic Training cohort P Validation cohort P
Benign (n = 33) Malignant (n = 46) Benign (n = 17) Malignant (n = 24)
Age (years) 0.008 0.009
 <40 10 (30.3) 4 (8.7) 6 (35.2) 2 (8.3)
 40–49 14 (42.4) 19 (41.3) 8 (47.1) 9 (37.5)
 50–59 8 (24.2) 11 (23.9) 3 (17.6) 4 (16.7)
 >=60 1 (3.0) 12 (26.1) 0 (0.0) 9 (37.5)
Family history of breast cancer, n (%) 0.693 1.000
 + 2 (6.1) 5 (10.9) 2 (11.8) 2 (8.3)
 – 31 (93.9) 41 (89.1) 15 (88.2) 22 (91.7)
History of biopsy, n (%) 0.171 1.000
 + 2 (6.1) 0 (0.0) 1 (89.7) 1 (4.2)
 – 31 (93.9) 46 (1.0) 16 (10.3) 23 (95.8)
Menstruation status, n (%) 0.001 0.002
 + 6 (76.8) 20 (49.3) 1 (89.7) 13 (30.3)
 – 27 (23.2) 26 (50.7) 16 (10.3) 11 (69.7)
BI-RADS (DM plus DBT), n (%) <0.001 <0.001
 0, 1, 2, 3 8 (24.2) 0 (0.0) 6 (35.3) 1 (4.2)
 4A, 4B, 4C 24 (72.7) 32 (69.6) 11 (64.7) 15 (62.5)
 5, 6 1 (3.0) 14 (30.4) 0 (0.0) 8 (33.3)
BI-RADS (MRI), n (%) <0.001
 1, 2, 3 18 (54.5) 0 (0.0) 8 (47.1) 0 (0.0)
 4, 5 15 (45.5) 46 (100.0) 9 (52.9) 24 (100.0)

BI-RADS, breast imaging reporting and data system; DM, digital mammography; DBT, digital breast tomosynthesis; MRI, magnetic resonance imaging.