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. 2021 Sep 23;11(9):e053791. doi: 10.1136/bmjopen-2021-053791

Table 3.

Sensitivity analyses for seroprevalence at extremes of test performance

Weighted seroprevalence, % (95% CI) Weighted seroprevalence adjusted for test performance, % (95% CI)
(Sensitivity 100.00%, specificity 99.63%)
Weighted seroprevalence adjusted for test performance, % (95% CI)
(Sensitivity 95.89%, specificity 99.90%)
Weighted seroprevalence adjusted for test performance, % (95% CI)
(Sensitivity 100.00%, specificity 99.05%)
Overall 36.9 (34.5 to 39.4) 36.7 (34.3 to 39.2) 38.4 (35.9 to 41.0) 36.3 (33.9 to 38.8)
Age (years)
 18–29 33.7 (30.1 to 37.6) 33.5 (29.8 to 37.4) 35.1 (31.3 to 39.1) 33.1 (29.4 to 37.0)
 30–49 36.3 (33.5 to 39.3) 36.1 (33.3 to 39.1) 37.8 (34.9 to 40.9) 35.7 (32.9 to 38.7)
 50–69 42.5 938.8 to 46.2) 42.3 (38.6 to 46.0) 44.3 (40.4 to 48.1) 41.9 (38.2 to 45.7)
 ≥70 45.3 937.8 to 53.0) 45.1 (37.6 to 52.8) 47.2 (39.4 to 55.2) 44.8 (37.2 to 52.5)
Gender
 Male 36.1 (33.5 to 38.9) 35.9 (33.3 to 38.7) 37.6 (34.9 to 40.5) 35.5 (32.9 to 38.3)
 Female 37.8 (34.5 to 41.30 37.6 (34.3 to 41.1) 39.4 (35.9 to 43.0) 37.2 (33.9 to 40.7)
Residence
 Urban 40.2 (36.3 to 44.1) 40.0 (36.1 to 43.9) 41.9 (37.8 to 45.9) 39.6 (35.7 to 43.6)
 Rural 35.5 (32.5 to 38.7) 35.3 (32.2 to 38.5) 37.0 (33.8 to 40.3) 34.9 (31.9 to 38.1)
Self-reported history of chronic disease
 Yes 43.2 (40.4 to 46.1) 41.9 (37.4 to 46.6) 43.6 (38.9 to 48.5) 41.3 (36.8 to 46.1)
 No 37.8 (36.4 to 39.1) 36.2 (33.7 to 38.9) 37.7 (35.1 to 40.5) 35.6 (33.1 to 38.3)
History of COVID-19-like symptoms
 Yes 52.1 (47.6 to 56.6) 47.4 (37.9 to 57.1) 49.4 (39.5 to 59.5) 46.9 (37.3 to 56.7)
 No 37.7 (36.4 to 38.9) 36.3 (33.9 to 38.8) 37.8 (35.3 to 40.4) 35.7 (33.3 to 38.2)
History of contact with a known COVID-19 case
 Yes 49.9 (45.2 to 54.5) 45.2 (38.3 to 52.2) 47.1 (39.9 to 54.4) 44.7 (37.7 to 51.7)
 No 37.9 (36.7 to 39.2) 36.5 (34.1 to 39.0) 38.0 (35.5 to 40.6) 35.9 (33.5 to 38.4)
Ever tested for COVID-19 (RT-PCR)
 Yes 44.4 (41.5 to 47.4) 41.0 (35.4 to 46.9) 42.7 (36.9 to 48.9) 40.4 (34.8 to 46.4)
 No 37.6 (36.2 to 38.9) 36.2 (33.5 to 39.0) 37.7 (34.9 to 40.6) 35.6 (32.9 to 38.4)
RT-PCR result (n=1088*)
 Positive 79.5 (73.0 to 84.9) 81.8 (74.8 to 87.1) 85.3 (78.0 to 90.8) 81.6 (74.6 to 87.0)
 Negative 37.8 (34.7 to 41.0) 38.8 (33.3 to 44.7) 40.4 (34.7 to 46.6) 38.2 (32.7 to 44.2)

RT-PCR, reverse-transcriptase PCR.