Table 2.
Univariable and multivariable linear regression analysis. Serum binding antibody levels in log transformed MFI values 21 days after the first vaccination in recently (n = 17) and earlier infected participants (n = 17), were compared to log transformed MFI values 28 days after the second vaccination in uninfected participants (n = 73). Neutralizing capacity in log transformed ID50 values in recently (n = 18) and earlier infected participants (n = 19) were compared to log transformed ID50 values 28 days after the second vaccination in uninfected participants (n = 51). Multivariable model includes participant sex and age as potential confounders.
| log MFI | Difference with uninfected (95% CI) | log ID50 | Difference with uninfected (95% CI) | |
|---|---|---|---|---|
| Univariable | ||||
| Uninfected | 7.59 | - | 7.57 | - |
| Recently infected | 8.33 | 0.74 (0.15–1.34) | 8.96 | 1.39 (0.82–1.95) |
| Earlier infected | 8.72 | 1.13 (0.53-1.72) | 9.41 | 1.84 (1.28–2.39) |
| Multivariable | ||||
| Uninfected | 7.63 | - | 7.24 | - |
| Recently infected | 8.31 | 0.68 (0.09–1.26) | 8.60 | 1.36 (0.80–1.92) |
| Earlier infected | 8.48 | 0.85 (0.22–1.47) | 8.91 | 1.67 (1.09–2.25) |
CI: Confidence interval, MFI: Mean Fluorescence Intensity, ID50: 50% Inhibitory Dilution.