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. 2021 Jun 9;21(5):392–402. doi: 10.1136/practneurol-2020-002782

Table 6.

Surgical intervention for trigeminal neuralgia34

Intervention Microvascular decompression Stereotactic radiosurgery Radiofrequency thermocoagulation Balloon compression Glycerol rhizolysis Internal neurolysis
                                Efficacy data
Number of studies 21 8 7 5 3 1
Total number of patients 5149 1168 4533 755 289 26
Mean/median follow-up 3–10.9 years 3.1–5.6 years 3–9.3 years 4.2–10.7 years 4.5–8 years 3.6 years
Pain free at follow-up (5) 62%–89% 30%–66% 26%–82% 55%–80% 19%–58% 72%
                                Complications (%)
Facial sensory changes 3 16 19 15 40 96
Corneal hypoaesthesia 0.3 0 6.6 0.7 6.6 0
Hearing loss 1.8 0 0.1 0 0.3 0
Motor weakness 0 0 6.2 4.5 1.7 0
Cranial nerve palsy 4.1 0.2 0.8 1.6 0 0
Meningitis 0.4 0 0.02 5.7 0 0
CSF leak 2 0 0.1 0 0 3.8
Anaesthesia dolorosa 0.02 0 0.6 0.1 0.7 3.9
Mortality 0.3 0 0 0 0 0

CSF, cerebrospinal fluid.