a, PSM was used to identify a matched cohort based on age, sex, BMI and outdoor temperature in the month of the index scan. b, Forest plots illustrate the association between brown fat status and use of antihypertensive drugs and statins in the propensity score-matched cohort. Circles and bars represent ORs and 95% CIs, respectively. c, Forest plots illustrate the association between brown fat status and site of neoplasm (based on ICD-O codes) in the propensity score-matched cohort. Circles and bars represent ORs and 95% CIs, respectively. d, Forest plots illustrate the association between brown fat status and cancer treatment in the propensity score-matched cohort. Circles and bars represent ORs and 95% CIs, respectively. ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; CCB, calcium channel blocker.