Fig. 1.
Schematic representation of the genomic architecture of the pks island (ca. 54 kb) present in Escherichia coli strain M1/5. The 19 genes within the island are coloured with respect to their function. The island codes for a phosphopantetheinyl transferase (clbA, in purple), a transcriptional autoactivator (clbR, in red), multiple core biosynthetic genes (clbB–clbL, clbN, clbO and clbQ in blue), a transporter (clbM, yellow), a peptidase (clbP, in green) and a resistance factor (clbS, orange).