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. 2021 Jun 15;7(6):000577. doi: 10.1099/mgen.0.000577

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© 2021 The Authors

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Fig. 4. — Structural variation of the colibactin and yersiniabactin-encoding chromosomal region in Escherichia coli, Enterobacter hormaechei, K. pneumoniae, K. aerogenes and C. koseri. The different genetic structures and chromosomal insertion sites of the colibactin and/or yersiniabactin determinants found within the three main structural classes are shown. The clb gene cluster (teal green), T4SS module (purple), ybt gene cluster (pink), integrase genes (green), the conserved sets of genes (Table S5) that are present up/downstream of the two polyketide determinants, classed into sets (blue boxes), and the Fe/Mn/Zn module (yellow) are shown. The number of genomes included in the tested set of genomes that harbour the different structural variants is indicated in parentheses. The colibactin–yersiniabactin chromosomal regions that do not conform to these major structures are as shown in Fig. S7.