Table 1.
Baseline recipient, donor and transplant characteristics of SLK transplants before and after policy implementation.
| SLK - Pre | SLK - Post | P-value | |
|---|---|---|---|
| Number | 1737 | 1702 | |
| Recipient characteristics | |||
| Age | 59 (51–64) | 59 (52–64) | 0.10 |
| Female Sex | 667 (38.4%) | 662 (38.9%) | 0.78 |
| Race | 0.13 | ||
| White | 1102 (63.4%) | 1037 (60.9%) | |
| Black | 266 (15.3%) | 246 (14.5%) | |
| Asian | 55 (3.2%) | 66 (3.9%) | |
| Other | 314 (18.1%) | 353 (20.7%) | |
| BMI | 26.6 (23.1–31.2) | 26.7 (23.5–31.3) | 0.25 |
| ICU status at transplant | 367 (21.1%) | 287 (16.9%) | <0.01 |
| Days on waitlist | 69 (16–273) | 88 (18–289) | 0.07 |
| MELD | 29 (23–36) | 28 (23–34) | <0.01 |
| Disabled functional status | 1001 (57.6%) | 916 (53.8%) | 0.03 |
| HCC | 224 (12.9%) | 185 (10.9%) | 0.07 |
| Diabetes mellitus | 746 (43.0%) | 735 (43.2%) | 0.89 |
| Portal vein thrombosis | 207 (12.0%) | 238 (14.1%) | 0.08 |
| History of SBP | 189 (10.9%) | 214 (12.6%) | 0.12 |
| TIPS | 169 (9.7%) | 138 (8.1%) | 0.11 |
| Hemodialysis | 1194 (68.7%) | 1191 (70.0%) | 0.44 |
| Previous liver transplant | 113 (6.5%) | 111 (6.5%) | 0.99 |
| Previous kidney transplant | 53 (3.0%) | 57 (3.3%) | 0.63 |
| Primary etiology of liver disease | <0.01 | ||
| NASH | 353 (21.2%) | 400 (24.5%) | |
| HCV | 359 (21.5%) | 234 (14.3%) | |
| EtOH | 475 (28.5%) | 498 (30.5%) | |
| Other | 480 (28.8%) | 501 (30.7%) | |
| Etiology of renal failure | 0.77 | ||
| ATN/HRS | 456 (26.3%) | 458 (26.9%) | |
| Diabetes mellitus | 824 (47.4%) | 788 (46.3%) | |
| Hypertension | 338 (19.4%) | 348 (20.5%) | |
| Other | 119 (6.9%) | 108 (6.3%) | |
| Donor characteristics | |||
| Age | 33 (24–45) | 34 (25–46) | 0.06 |
| Female Sex | 667 (38.4%) | 662 (38.9%) | 0.78 |
| BMI | 26.0 (23.0–29.9) | 26.4 (23.1–30.4) | 0.09 |
| Creatinine (mg/dL) | 0.90 (0.70–1.20) | 0.90 (0.70–1.25) | 0.76 |
| Bloodstream Infection | 182 (10.5%) | 162 (9.5%) | 0.36 |
| LDRI | 1.81 (1.62–2.09) | 1.84 (1.64–2.13) | 0.07 |
| KDPI (%) | 28 (12–50) | 30 (13–53) | 0.06 |
| DCD | 108 (6.2%) | 115 (6.7%) | 0.53 |
| Cause of death - CVA | 391 (22.5%) | 337 (19.8%) | 0.06 |
| Transplant details | |||
| CIT - Liver (hours) | 6.0 (4.8–7.5) | 5.8 (4.7–7.2) | 0.01 |
| CIT - Kidney (hours) | 10.2 (7.8–14.0) | 10.5 (8.1–16.1) | <0.01 |
Values are listed as median +/− interquartile range unless otherwise stated
BMI, body mass index; cPRA, calculated panel reactive antibodies; ATN, acute tubular necrosis; HRS, hepatorenal syndrome; CVA, cerebrovascular accident; KDPI, Kidney Donor Profile Index.