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. 2021 Sep 16;22(5):1312. doi: 10.3892/etm.2021.10747

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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BS supplementation alleviates alcohol-induced liver inflammation. (A) Protein expression of TLR4. (B) Values of TLR4 protein expression were normalized to those of β-actin as the control. (C) Hepatic gene expression of proinflammatory cytokines TNF-α, NF-κβ and IL-6 and the chemokine MCP-1. (D) Serum IL-6 levels. Data are presented as the mean ± standard deviation of at least three independent experiments. ^#P<0.05; ^##P<0.01. BS, B. subtilis supplementation; TLR4, toll-like receptor 4; TNF-α, tumor necrosis factor alpha; NF-κB, nuclear factor-κB; MCP-1, monocyte chemoattractant protein-1; Ctrl, control; EtOH, ethyl alcohol.