Fig. 2.

Observed individual and predicted growth trajectories for the 3-class (A) CDR-SB¹ and (B) FAQ² models³. CDR-SB, Clinical Dementia Rating Scale-Sum of Boxes; FAQ, Functional Activities Questionnaire. ¹ CDR-SB score ranges from 0 to 18 in 0.5 increments. Higher values indicate worse cognition: 0 = Normal; 0.5 –4.0 = Questionable cognitive impairment; 4.5 –9.0 = Mild dementia; 9.5 –15.5 = Moderate dementia; 16.0 –18.0 = Severe dementia. ² FAQ score ranges from 0 to 30. Higher values indicate worse function. A cutoff of 9 (dependent on 3 or more activities) is recommended to indicate impaired function and possible cognitive impairment. ³ These models were run using the latent class mixed models (lcmm) package in R. Trajectories are based on lcmm’s predictY function.