Table 1.
C | MCI | AD | *p HC versus MCI | * HC versus AD | p | |
Sample number | 40 | 20 | 20 | |||
Sex (F/M) | 19/21 | 11/9 | 8/12 | ns | ns | |
Age | 75.3 | 77.8 | 78.0 | ns | ns | |
MMSE | 28.6 | 26.6 | 21.1 | 0.018 | < 0.0001 | |
APOE ɛ4 allele positive (%) Homozygous E4/E4 % | 7/40 (17.5%) 0% | 11/20 (55%) 0% | 10/20 (50%) 20% | |||
Vitamin B12 (pmol/L) | 303.8±14.5 | 402.5±42.6 | 395.6±27.6 | 0.02 | 0.03 | |
Folate (nmol/L) | 30.1±1.5 | 34.5±2.2 | 33.9±2.9 | ns | ns | |
Homocysteine (μmol/L) | 14.1±0.6 | 14.1±0.9 | 15.6±1.2 | ns | ns | |
Vitamin D3 (nmol/L) | 69.1±3.6 | 89.2±5.8 | 70.7±4.3 | 0.006 | ns | |
Cholesterol (mmol/L) | 4.79±0.19 | 4.55±0.32 | 4.98±0.29 | ns | ns | |
Triglyceride (mmol/L) | 1.43±0.10 | 1.47±0.15 | 1.19±0.10 | ns | ns | |
HDL-cholesterol (mmol/L) | 1.50±0.05 | 1.71±0.15 | 1.89±0.15 | ns | 0.02 | |
LDL-cholesterol (mmol/L) | 2.65±0.18 | 2.06±0.22 | 2.32±0.25 | ns | ns | |
Non HDL-cholesterol (mmol/L) | 3.30±0.20 | 3.04±0.36 | 2.89±0.22 | ns | ns | |
CRP (mg/L) | 2.33±0.39 | 1.76±0.39 | 1.41±0.32 | ns | ns |
*Bonferroni post-hoc test.