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. 2021 Sep 23;8(2):e001765. doi: 10.1136/openhrt-2021-001765

Table 2.

Crude and adjusted clinical outcomes

Both ECG-based and echo-based LVH
Number of patients with event/N of patients at risk (cumulative 3-year incidence(%))
Only echo-based LVH
Number of patients with event/N of patients at risk (cumulative 3-year incidence(%))
Only
ECG-based LVH
Number of patients with event/N of patients at risk (cumulative 3-year incidence(%))
No LVH
Number of patients with event/N of patients at risk (cumulative 3-year incidence(%))
Variables Unadjusted Adjusted
HR
(95% CI)
P value HR
(95% CI)
P value
Primary endpoint
A composite of all-cause death or MACE 34/131 (32.0) 45/156 (33.8) 65/409 (19.2) 307/2516 (15.7) Both ECG- and echo-based LVH 2.33 (1.70 to 3.19) <0.001 1.63 (1.16 to 2.28) 0.005
Only echo-based LVH 2.21 (1.64 to 2.97) <0.001 1.68 (1.23 to 2.30) 0.001
Only ECG-based LVH 1.12 (0.87 to 1.44) 0.38 1.09 (0.85 to 1.41) 0.49
No LVH 1 (reference) 1 (reference)
Secondary endpoints
All-cause death 16/131 (15.8) 21/156 (15.9) 36/409 (10.7) 203/2516 (10.4) Both ECG-based and echo-based LVH 1.59 (1.03 to 2.45) 0.04 1.43 (0.90 to 2.27) 0.13
Only echo-based LVH 1.39 (0.91 to 2.13) 0.13 1.22 (0.78 to 1.89) 0.39
Only ECG-based LVH 0.93 (0.67 to 1.29) 0.66 0.94 (0.68 to 1.30) 0.71
No LVH 1 (reference) 1 (reference)
MACE 23/131 (22.5) 26/156 (21.8) 38/409 (11.8) 139/2516 (7.5) Both ECG-based and echo-based LVH 3.48 (2.35 to 5.16) <0.001 1.91 (1.25 to 2.91) 0.003
Only echo-based LVH 2.89 (1.95 to 4.28) <0.001 1.86 (1.23 to 2.81) 0.003
Only ECG-based LVH 1.45 (1.04 to 2.03) 0.03 1.38 (0.98 to 1.93) 0.06
No LVH 1 (reference) 1 (reference)

LVH, left ventricular hypertrophy; MACE, major adverse cardiovascular events.