Table 2.
Subject characteristics and serum sex steroids during experimental visits
| GnRHant | GnRHant + E2 | P Value | |
|---|---|---|---|
| Demographic and hemodynamic measurements | |||
| Mass, kg | 68 ± 10 | 68 ± 10 | 0.412 |
| Systolic BP, mmHg | 109 ± 9 | 107 ± 8 | 0.332 |
| Diastolic BP, mmHg | 67 ± 6 | 67 ± 6 | 0.504 |
| MAP, mmHg | 81 ± 7 | 80 ± 7 | 0.399 |
| Hormones, pg/mL | |||
| Estradiol, serum | 68 ± 63 | 83 ± 65 | 0.004 |
| Progesterone, serum | 0.75 ± 0.84 | 0.62 ± 0.90 | 0.191 |
| Endothelin-1, plasma | 1.30 ± 0.58 | 1.22 ± 0.30 | 0.577 |
Values are means ± SD; n = 15 subjects. BP, blood pressure; E2, estradiol; GnRHant, gonadotropin-releasing hormone antagonist; MAP, mean arterial pressure. P values are from paired t test comparisons.