Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Acid sphingomyelinase was measured as candidate defect in 95RD414 and in three controls (CABMHF3, a case with no detected pathogenic changes in NPC1 and GM23248 and GM23249, fibroblasts from two apparently normal individuals). Cholesterol esterification assays and filipin staining on all four lines were within control values. Error bars indicate SEM.
