Table 2.
Factors affecting overall survival of participants
|
Factors
|
Univariate
|
Multivariate
|
||
|
OR (95%CI)
|
P
value
|
OR (95%CI)
|
P
value
|
|
| Age (yr) | 1.027 (1.019–1.035) | < 0.001 | 1.031 (1.023–1.039) | < 0.001 |
| Sex | 0.704 (0.592–0.836) | < 0.001 | 0.711 (0.598–0.845) | < 0.001 |
| Surveillance intensity | 1.650 (1.400–1.945) | < 0.001 | 1.531 (1.295–1.808) | < 0.001 |
| Differentiation | ||||
| WD/MD | Ref. | Ref. | ||
| PD/SRC/MUC | 1.832 (1.424–2.356) | < 0.001 | 1.660 (1.285–2.143) | < 0.001 |
| (y) pT stage | ||||
| 0–2 | Ref. | Ref. | ||
| 3–4 | 1.937 (1.491–2.516) | < 0.001 | 1.461 (1.111–1.921) | 0.007 |
| (y) pN stage | ||||
| 1c | Ref. | Ref. | ||
| 1 | 5.136 (0.721–36.571) | 0.102 | 4.754 (0.667–33.906) | 0.12 |
| 2 | 9.322 (1.308–66.457) | 0.026 | 7.067 (0.988–50.556) | 0.051 |
| Lymphovascular invasion | 1.607 (1.365–1.891) | < 0.001 | 1.256 (1.057–1.491) | 0.01 |
| Perineural invasion | 1.818 (1.535–2.154) | < 0.001 | 1.466 (1.224–1.755) | < 0.001 |
| Resection margin1 | 1.972 (1.360–2.860) | < 0.001 | 1.603 (1.097–2.341) | 0.015 |
1
Resection margin indicated circumferential resection margin, and were calculated with rectal cancer patients. OR: Odds ratio; CI: Confidence interval; Ref: Reference; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated; SRC: Signet ring cell type; MUC: Mucinous carcinoma.