Table 3.
Factors affecting recurrence-free interval of participants
| Factors |
Univariate
|
Multivariate
|
||
|
OR (95%CI)
|
P
value
|
OR (95%CI)
|
P
value
|
|
| Age (yr) | 0.995 (0.987–1.002) | 0.165 | 0.999 (0.991–1.006) | 0.715 |
| Sex | 0.907 (0.765–1.076) | 0.262 | ||
| Surveillance intensity | 2.218 (1.870–2.632) | < 0.001 | 1.999 (1.680–2.377) | < 0.001 |
| Differentiation | ||||
| WD/MD | Ref. | Ref. | ||
| PD/SRC/MUC | 1.507 (1.151–1.974) | 0.003 | 1.287 (0.979–1.694) | 0.071 |
| (y) pT stage | ||||
| 0–2 | Ref. | Ref. | ||
| 3–4 | 2.118 (1.610–2.785) | < 0.001 | 1.596 (1.197–2.127) | 0.001 |
| (y) pN stage | ||||
| 1c | Ref. | Ref. | ||
| 1 | 2.737 (0.682–10.989) | 0.156 | 2.501 (0.621–10.063) | 0.197 |
| 2 | 5.260 (1.308–21.156) | 0.019 | 3.813 (0.943–15.413) | 0.060 |
| Lymphovascular invasion | 1.460 (1.236–1.724) | < 0.001 | 1.143 (0.957–1.364) | 0.140 |
| Perineural invasion | 1.949 (1.641–2.313) | < 0.001 | 1.431 (1.192–1.719) | < 0.001 |
| Resection margin1 | 2.192 (1.529–3.144) | < 0.001 | 1.565 (1.083–2.262) | 0.017 |
1
Resection margin indicated circumferential resection margin, and were calculated with rectal cancer patients. OR: Odds ratio; CI: Confidence interval; Ref: Reference; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated; SRC: Signet ring cell type; MUC: Mucinous carcinoma.