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. 2021 Sep 27;13(9):1012–1024. doi: 10.4240/wjgs.v13.i9.1012

Table 4.

Factors affecting post-recurrence survival of participants

Factors
Univariate
Multivariate
OR (95%CI)
P value
OR (95%CI)
P value
Age (yr) 1.015 (1.007–1.024) < 0.001 1.015 (1.006–1.024) 0.001
Sex 0.824 (0.676–1.004) 0.054 0.842 (0.688–1.032) 0.098
Image intensity 0.971 (0.799–1.179) 0.767
Differentiation
WD/MD Ref. Ref.
PD/SRC/MUC 2.632 (1.779–3.137) < 0.001 2.072 (1.553–2.766) < 0.001
(y) pT stage
0–2 Ref.
3–4 1.146 (0.833–1.576) 0.401
(y) pN stage
1c Ref.
1 2.139 (0.300–15.256) 0.448
2 3.363 (0.471–24.009) 0.226
Lymphovascular invasion 1.456 (1.204–1.760) < 0.001 1.152 (0.940–1.412) 0.174
Perineural invasion 1.384 (1.141–1.677) 0.001 1.284 (1.045–1.579) 0.018
Resection margin1 1.416 (0.966–2.075) 0.075 1.266 (0.856–1.871) 0.237
Curative resection 0.296 (0.229–0.381) < 0.001 0.331 (0.255–0.428) < 0.001
1

Resection margin indicated circumferential resection margin, and were calculated with rectal cancer patients. OR: Odds ratio; CI: Confidence interval; Ref: Reference; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated; SRC: Signet ring cell type; MUC: Mucinous carcinoma.