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. 2021 Sep 9;12:723010. doi: 10.3389/fimmu.2021.723010

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Copyright © 2021 Lazar, Kussmann, Pawelec, Pöschel, Goelz, Hamprecht and Wistuba-Hamprecht

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Breast milk lymphocyte subpopulations of 15 HCMV seropositive and seronegative mothers. Frequencies within CD45+ leukocytes of (A) T cells (CD45+ CD3+ CD56-), (B) activated T cells (CD45+ CD3+ HLA-DRdim), (C) NKT-like cells (CD45+ CD3+ CD56+), (D) NK cells (CD45+CD3-CD56dim), (E) B cells (CD45+ CD3- CD19+) of HCMV-IgG- and IgG+ mothers at two time points (T1: 6-22, T2 39-108 days p.p.). Mothers with consecutive samples are color coded (blue: mother 7, red: mother 14 and green: mother 15). Statistical analysis was performed by Mann-Whitney U-test. The arrow in (B) highlights very high HLA-DR expression on CD3 T cells of one mother.